Cancer is one of the most feared diseases we have today and can happen to anyone at any age. Around 5 to 10 percent of all cancer cases are through inherited genetic mutations. CGx NGS tests are given to look for specific inherited changes in an individual’s genetic makeup, which may put them at risk of developing harmful diseases such as cancer. This test helps determine a person’s risk and appropriate therapy options for the disease. There are many benefits of CGx testing and finding the proper candidates is key. Learn more about the advances of a targeted next-generation sequencing CGx test in Healthcare.
Cancer Genomics Testing, or CGx, is a genetic test carried out to assist healthcare practitioners in identifying a patient’s risk of developing certain types of cancer. The test analyzes an individual’s DNA to look for specific variants that may make one susceptible to developing hereditary cancers. Through the test, healthcare providers can know whether the patient being tested is likely to benefit from specific cancer drugs or not. Most importantly, the test provides cancer patients with information and the opportunity to make proper care decisions.
The standard cancer treatment is performed mainly through chemotherapy, surgery, radiation therapy, or sometimes a combination. However, in some cases the addition of targeted therapy can increase outcomes. Targeted therapy is achieved utilizing CGx testing results allowing healthcare practitioners can now administer cancer drugs and begin therapy that will most likely match, enabling cancer patients to benefit fully from the treatment.
Genetic mutations are alterations in the DNA genetic makeup. Mutations can be inherited or occur due to environmental factors such as exposure to toxins or radiation. It is through a mutation that there is an increased production of protein present in the tumor tissue, which tends to spread and become resistant to standard treatment like chemotherapy. CGx tests detect the DNA mutations and helps determine if an individual will or will not respond to a particular targeted therapy. Some patients, based on their genetic makeup are drug resistance, and may not respond to certain therapy treatment options.
CGx testing becomes necessary when those suffering from various cancers fail to respond to chemotherapy and, generally, to patients with any type of cancer. The simple cheek swab is usually done only once, but in some cases, when the patient’s tumor continues to progress while under therapy, testing is done more than once. Multiple NGS tests may be performed more than once, to identify if a mutation has occurred, leading to resistance during treatment.
CGx testing should be performed on everyone with cancer, family history of cancer or idiopathic symptoms. Testing will help healthcare practitioners identify the right targeted therapy that will be useful for cancer patients in general.
NGS CGx tests is a procedure that requires specialized skills and equipment. Tesis Biosciences can analyze targeted CGx tests in our clinical diagnostic centers, where you will receive accurate and timely results. Contact us today if you need more information or are a candidate for the CGx testing.